Abstract Background In recent years, experience on the application of adaptive designs in confirmatory clinical trials has accumulated.Although planning such trials comes at the cost of additional operational complexity, adaptive designs offer the benefit of flexibility to update trial design and objectives as data accrue.In 2007, the European Medi
Drug-induced acute kidney injury (DI-AKI) is one of the leading causes of kidney injury, is associated with high mortality and morbidity, and limits amina muaddi scarpe trasparenti the clinical use of certain therapeutic or diagnostic agents, such as antineoplastic drugs, antibiotics, immunosuppressants, non-steroidal anti-inflammatory drugs, and c
IntroductionThis study explores the integration of financial stability regulation in professional soccer within the framework of sport governance, focusing on the German context.The research examines how financial regulations influence key governance principles such as accountability, transparency, and sustainability, while also addressing the chal
Alicia Fernandez-Fernandez,1,2 Romila Manchanda,1,3 Denny Carvajal,1,4 Tingjun Lei,1,5 Supriya Srinivasan,1 Anthony J McGoron11Biomedical Engineering Department, Florida International University, Miami, FL, USA; 2Physical Therapy Department, Nova Southeastern University, Fort Lauderdale, FL, USA; 3Chemistry Department, Galgotias University, Greater